Breast Cancer Gene-Expression Miner v4.5
(bc-GenExMiner v4.5)
HOME
ANALYSIS
CORRELATION
Targeted
Exhaustive
Chromosomal location
EXPRESSION
Targeted
Exhaustive
Customised
PROGNOSTIC
Targeted
Exhaustive
Intrinsic molecular subtypes
Basal-like/TNBC
TUTORIAL
FLOWCHART
CORRELATION
Targeted
Exhaustive
Chromosomal location
EXPRESSION
Targeted
Exhaustive
Customised
PROGNOSTIC
Targeted
Exhaustive
Intrinsic molecular subtypes
Basal-like/TNBC
BACKGROUND
DATA CONTENT
Published annotated data
Published genomic data
Intrinsic molecular subtypes classification
DATA PRE-PROCESSING
DATA ANALYSIS
Statistical analyses
Statistical tests
Graphic illustrations
WHAT'S NEW?
HOW TO CITE US?
HOME
ANALYSIS
CORRELATION
Targeted
Exhaustive
Chromosomal location
EXPRESSION
Targeted
Exhaustive
Customised
PROGNOSTIC
Targeted
Exhaustive
Intrinsic molecular subtypes
Basal-like/TNBC
TUTORIAL
FLOWCHART
CORRELATION
Targeted
Exhaustive
Chromosomal location
EXPRESSION
Targeted
Exhaustive
Customised
PROGNOSTIC
Targeted
Exhaustive
Intrinsic molecular subtypes
Basal-like/TNBC
BACKGROUND
DATA CONTENT
Published annotated data
Published genomic data
Intrinsic molecular subtypes classification
DATA PRE-PROCESSING
DATA ANALYSIS
Statistical analyses
Statistical tests
Graphic illustrations
WHAT'S NEW?
HOW TO CITE US?
Customised expression analysis
Enter input genes to analyse (reference in second textbox):
GENE EXPRESSION DATA
First, choose your gene expression data. Information about cohorts :
microarrays
,
Affymetrix
®,
METABRIC
,
TCGA
or SCAN-B (aka GSE81540 =
GSE81538
+
GSE96058
)
This is your target gene. Its expression values will be split by another gene (see below).
Nota bene:
only
Affymetrix®
U133 Plus 2.0 have been retained for this analysis module (if Affymetrix data are chosen).
*: see actualised web databases (e.g.:
GeneCards
,
Ensembl
,
HGNC
,
NCBI Gene
...)
DNA microarrays
All
(n = 10 001)
Affymetrix®
(n = 2 151)
METABRIC
(n = 1 980)
RNA-seq
All
(n = 4 712)
TCGA
(n = 1 034)
SCAN-B
(n = 3 678)
SPLITTING GENE
This gene will be dichotomised according to chosen splitting criterion expression value (option below), and will be the splitting criteria of the tested gene (first textbox).
Fill the textbox with actualised* gene symbol that will be your splitting criteria.
*: see actualised web databases (e.g.:
GeneCards
,
Ensembl
,
HGNC
,
NCBI Gene
...)
DISCRETISATION
Choose one of the radio button to select which splitting method you want to explore for expression study:
"mediane": 2 groups split at 50%,
"tertile": 3 groups split at 33%,
"quartile": 4 groups split at 25%,
"optimal": 2 groups split at the best cut-off (
more details
)
"custom percentile": 2 groups split at the user cut-off.
Splitting criterion:
median
tertile
quartile
optimal
customised
percentile
Submit
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Last update
June 22, 2020
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